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恶性组织细胞增生症(Malignant his-tiocytosis,恶组)是单核巨噬细胞系统的组织细胞呈进行性浸润性增生的恶性疾病,可累及多数器官组织。本病引起的肝脏损害甚为常见,据我们尸检材料统计,96%的病例有肝内浸润,临床上可因肝肿大、黄疸和进行性肝功衰竭而误诊为原发性肝脏疾病。为此,我们在25例尸检材料的系统研究基础上,与临床资料相结合,总结恶组时肝损害的临床及病理特点,以便与肝病相鉴别,提高对本病的认识,减少误诊。
Malignant his-tiocytosis (Malignant his-tiocytosis, evil group) is a malignant disease of progressive infiltrative hyperplasia of the tissue cells of the mononuclear macrophage system, which can affect most organ tissues. Liver damage caused by the disease is very common, according to our autopsy material statistics, 96% of cases have intrahepatic infiltration, clinically due to hepatomegaly, jaundice and progressive liver failure misdiagnosed as primary liver disease. Therefore, based on the systematic study of 25 autopsy materials, we combined the clinical data and summarized the clinical and pathological features of liver damage in the malignant group so as to differentiate the liver disease, improve the understanding of the disease and reduce the misdiagnosis.