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在急性毒性、致灾变试验及亚慢性毒性试验的基础上，应用大鼠胚胎形成发育，胎鼠外观、内脏、骨骼畸形等指标进行大鼠传统致畸试验，研究了新资源食品益肝茶的致畸作用。设外0.3g／kg、3g／kg、30g／kg体重三个实验组，以浓缩鱼肝抽0．5ml／kg体重（相当于VA2500iu、VD2500iu／kg体重）为阳性对照物，蒸馏水为阴性对照组。结果表明，益肝茶对孕鼠无母体毒性、无胚胎毒性和致畸作用。
On the basis of acute toxicity, catastrophic change test and subchronic toxicity test, the traditional teratogenicity test of rats was carried out based on the development of rat embryo, the appearance of fetus, viscera and skeletal deformity, and the research on the new resource food Yigancha Teratogenic effect. Three experimental groups (0.3g / kg, 3g / kg and 30g / kg body weight) were set up as the positive control and the distilled water was the negative control with the concentrate of fish liver pumping 0.5ml / kg body weight (equivalent to VA2500iu, VD2500iu / kg body weight) group. The results show that Yigan tea on pregnant rats without maternal toxicity, embryo toxicity and teratogenic effects.