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目的探讨0~8个月龄婴儿麻疹胎传抗体水平的分布情况,为医院提高婴儿麻疹的预防能力提供参考依据。方法抽取我院在2012年7月至2013年4月收治的800例婴儿作为研究对象,并通过应用血凝抑制试验(HI),对新生儿和3、6、8个月龄婴儿的血清中麻疹免疫球蛋白G抗体水平分布情况进行测定。结果经研究,了解到全组0~8个月龄婴儿的麻疹胎传抗体阳性率,在新生儿期间为100%(210/210),在3个月龄时为59.15%(126/213),在6个月龄时为31.87%(58/182),在8个月龄时为16.41%(32/195),比较差异有统计学意义(P<0.05)。结论 0~8个月龄婴儿麻疹胎传抗体水平随着月龄的增大而出现逐渐下降的趋势,且以4~8个月龄的婴儿为麻疹易感群,需要医院予以充分重视,同时可考虑将麻疹疫苗首次免疫时间提前至出生4~6个月龄之间。
Objective To investigate the distribution of fetal antibody levels in measles cases of 0-8 months old infants and provide references for the hospital to improve the preventive ability of measles in infants. Methods A total of 800 infants admitted from July 2012 to April 2013 in our hospital were enrolled in this study. Serum levels of newborns, 3,6,8 months old infants The level of measles immunoglobulin G antibody distribution was determined. Results The study revealed that the prevalence of measles OBR in infants aged 0-8 months was 100% (210/210) during the neonatal period and 59.15% (126/213) at 3 months of age , 31.87% (58/182) at 6 months of age and 16.41% (32/195) at 8 months of age, the difference was statistically significant (P <0.05). Conclusions The levels of measles fetal antibodies in 0-8 month-old infants decreased gradually with the increase of age, and the measles-susceptible infants aged 4-8 months old needed full attention from the hospital. Measles vaccine may be considered for the first time of immunization to birth 4 to 6 months of age.