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目的观察运用经尿道电切术治疗膀胱肿瘤的临床疗效。方法选取于我院就诊的171例膀胱肿瘤患者,随机分为治疗组91例和对照组80例,治疗组患者予以经尿道电切术方法治疗膀胱肿瘤,对照组患者采用开放手术治疗方式,两组患者术后均予以50 ml生理盐水中加入40 mg丝裂霉素进行膀胱灌注腔内化疗,1次/周,持续治疗2个月。结果在手术时间、术中出血量及平均住院时间三个治疗情况方面,治疗组均显著小于对照组(P均<0.05),差异有统计学意义;复发率方面,进行为期1年的随访后,治疗组复发20例,复发率为21.98%;对照组复发25例,复发率为31.25%,两组比较差异不具有统计学意义(P>0.05)。结论相比于传统开放式手术方式,经尿道电切术具有手术创伤小、患者痛苦小、术中出血少且恢复时间短等优点,且疗效显著,术后复发率较低,值得临床推广应用。
Objective To observe the clinical efficacy of transurethral resection of bladder tumor. Methods A total of 171 bladder cancer patients treated in our hospital were randomly divided into treatment group (n = 91) and control group (n = 80). The patients in the treatment group were treated by transurethral resection of the bladder tumor, while the control group were treated by open surgery Patients were treated with intraperitoneal chemotherapy of intravesical instillation with 40 mg of mitomycin in 50 ml of normal saline once a week for 2 months after operation. Results In terms of operation time, intraoperative blood loss and average length of stay, the treatment group was significantly smaller than the control group (all P <0.05), and the difference was statistically significant. In terms of the recurrence rate, after a one-year follow-up , The treatment group relapsed in 20 cases, the recurrence rate was 21.98%; control group 25 cases of recurrence, the recurrence rate was 31.25%, the difference between the two groups was not statistically significant (P> 0.05). Conclusion Compared with the traditional open surgical approach, transurethral resection has the advantages of less trauma, less pain, less intraoperative bleeding and shorter recovery time, and has a significant effect and a low recurrence rate, which is worthy of clinical application .