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目的 分析基于临床护理路径的中医辨证施护在膝关节骨关节炎中的应用效果，为临床护师选择合理护理方案提供参考。方法 选择2017年8月至2019年7月沈阳市骨科医院收治的102例膝关节骨关节炎患者为研究对象，依据随机数字表法，将研究对象分成试验组和对照组（每组51例）。对照组给予常规护理，试验组给予基于临床护理路径的中医辩证施护，比较两组患者的临床总有效率、膝关节功能恢复情况、膝关节疼痛改善情况、临床指标、生活质量评分以及护理满意度。结果 试验组患者临床治疗总有效率为98.04%，远高于对照组的82.35%（“,”Objective To analyze the application effect of TCM syndrome differentiation nursing based on clinical nursing path in knee osteoarthritis，and to provide reference for clinical nurses to choose reasonable nursing scheme. Methods A total of 102 patients with knee osteoarthritis treated in Shenyang orthopedic hospital from August 2017 to July 2019 were selected as the research objects. According to the random number table method，the research objects were divided into experimental group and control group (51 cases in each group). The control group was given routine nursing，and the experimental group was given TCM dialectical nursing based on clinical nursing path. The total clinical effective rate， knee function recovery，knee pain improvement， clinical index comparison， quality of life score and nursing satisfaction were compared between the two groups. Results The total effective rate of clinical treatment in the experimental group was 98.04%， much higher than 82.35% in the control group(P＜0.05).There was no significant difference in knee pain score between the experimental group and the control group before nursing (P＞0.05). After nursing， the improvement of knee pain in the experimental group was significantly better than that in the control group(P＜0.05). The re-admission rate， second re-admission rate，health knowledge mastery， and compliance status of patients in the experimental group were better than those in the control group， and the hospital stay was shorter than that in the control group， P＜0.05. The scores of quality of life in the experimental group were higher than those in the control group，indicating that the treatment recovery effect of the experimental group was better and had a positive impact on the patients\' daily life; There was no significant difference in Lysholm knee score between the two groups before nursing (P＞0.05). After 8 weeks of nursing， the Lysholm knee score of the two groups was higher than that before nursing (P＜0.05). The nursing satisfaction of patients in the experimental group was 96.08%， which was higher than 82.35% in the control group (P＜0.05). Conclusion In the nursing of patients with knee osteoarthritis， the dialectical nursing method of traditional Chinese medicine based on clinical nursing path can promote the better recovery of knee function， and the patient satisfaction is high， which is worthy of reference.