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本文前瞻性地研究了使用非类固醇抗炎药(NSAID_S)者的幽门螺旋菌(HP)感染率,及其与胃部并发症发生和严重程度的关系。病人与方法:111俐病人参加本研究。66例服用NSAID_S者为实验组,包括骨关节炎35例,类风湿性关节炎或骨关节硬化症21例,因其他原因而服用NSAID_S者10例。分为三个亚组:Ⅰ组28例,内镜下没有病变;Ⅱ组26例,有内镜下胃十二指肠病变;Ⅲ组12例,有内镜下病变伴出血。对照组45例未服用NSAID_S,无上消化道症状及胃十二指肠病变。各组间在年
This study prospectively investigated the prevalence of Helicobacter pylori (HP) in non-steroidal anti-inflammatory drugs (NSAID_S) and its relationship with the incidence and severity of gastric complications. Patients and Methods: 111 patients were enrolled in this study. Sixty-six patients taking NSAID-S were included in the experimental group, including 35 cases of osteoarthritis, 21 cases of rheumatoid arthritis or osteoarthritis, and 10 cases of NSAID-3 due to other reasons. Divided into three subgroups: 28 cases of group Ⅰ, no lesions under endoscopy; Ⅱ group of 26 cases, with endoscopic gastroduodenal lesions; Ⅲ group of 12 cases, with endoscopic lesions with bleeding. Control group, 45 patients did not take NSAID_S, upper gastrointestinal symptoms and gastroduodenal lesions. Between the groups in years