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斜茎獐牙菜(Swertia Patens Burk)为龙胆科獐牙菜属植物,又名金沙青叶胆、小儿腹痛草,彝药名“落孺疴”其意为苦得很,我省彝族人民用其全草治疗消化不良、腹痛、牙痛、沿用历史已久。我们对该植物进行了实验研究,从其全草中分离得到齐墩果酸及獐牙菜苦甙。本所实验证明:齐墩果酸对大鼠由四氯化碳引起的肝损伤有保护作用;獐牙菜苦甙有明显的解除平滑肌痉挛作用。近三年来,我所对斜茎獐牙菜的植物学、生药学、有效成分的提取、分离、结构鉴定、药理、毒理等方面进行了研究,其中主要有效成分——獐牙菜苦甙作为解止痛新药已于1983年12月
Swertia Patens Burk is a plant belonging to the Gentianaceae Swertia genus. It is also known as Jinshaqingye, a young child with abdominal pain. With its whole plant to treat indigestion, abdominal pain, toothache, has a long history. We conducted an experimental study on this plant and isolated oleanolic acid and swertia sclerophylla from its whole plant. Our experiments proved that oleanolic acid has a protective effect on carbon tetrachloride-induced liver damage in rats; Swertia officinalis significantly relieved smooth muscle spasm. In the past three years, we have studied botany, pharmacognosy, extraction, separation, structure identification, pharmacology, and toxicology of Swertia sphaerocephala. Among them, the main active ingredient is Swertia sclerophylla. As an antidote for pain relief, it was established in December 1983