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报道了沙蚕毒素类农药──巴丹、易卫杀经口灌胃后，在大鼠体内代谢最终产物的研究。采用高效薄层色谱法（ＨＰＴＬＣ）及气相色谱－质谱法（ＧＣ－ＭＳ）分析大鼠尿中代谢物。两种鼠尿样品的ＴＬＣ图上均呈现七个斑点，与杀虫双及沙蚕毒素最终代谢物Ｒｆ值一致。ＧＣ－ＭＳ的分析结果与杀虫双及沙蚕毒素的鼠尿代谢物轮廓相符。结果提示巴丹、易卫杀和杀虫双在大鼠体内代谢的途径有共同特征，即经口灌胃后，在体内首先转化成沙蚕毒素，继而按沙蚕毒素的形式进行代谢。
Reported nereistoxin pesticides ─ ─ Bataan, Yi Wei kill oral administration of gavage, the metabolism of the final product in rats. Rat urinary metabolites were analyzed by high performance thin layer chromatography (HPTLC) and gas chromatography-mass spectrometry (GC-MS). There were seven spots on the TLC images of the two rat urine samples, consistent with the Rf values of the final metabolite of the insecticidal bis and Nereistoxin. The results of GC-MS analysis are in agreement with the profiles of rat urine metabolites of the insecticidal bisoprotocin and nereistoxin. The results suggest that Badan, easy to kill and insecticidal double metabolic pathways in rats have common characteristics, that is, after oral gavage, the body first converted to Nereis toxin, followed by Nereis toxin in the form of metabolism.