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目的:观察加味柴胡疏肝散联合硝酸甘油片治疗冠心病心绞痛的临床疗效。方法:选取100例心血瘀阻型冠心病心绞痛患者为研究对象,随机分为对照组和观察组各50例。对照组在硝酸甘油片治疗基础上加用复方丹参片,观察组在硝酸甘油片治疗基础上加用加味柴胡疏肝散。2组疗程均为20天。比较2组的临床疗效和治疗前后血浆脑钠肽(BNP)的变化情况。结果:总有效率观察组为96.0%,对照组为86.0%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组血浆BNP水平均低于治疗前(P<0.05),观察组BNP水平低于对照组(P<0.05)。结论:在硝酸甘油片治疗基础上,采用加味柴胡疏肝散治疗心血瘀阻型冠心病心绞痛患者的临床疗效优于复方丹参片。
Objective: To observe the clinical effects of Modified Chaihu Shugan Powder combined with nitroglycerin in the treatment of angina pectoris of coronary heart disease. Methods: 100 cases of patients with heart-blood stasis type of coronary heart disease angina pectoris were randomly divided into control group and observation group of 50 cases. The control group in the treatment of nitroglycerin plus compound Danshen tablets, the observation group in the treatment of nitroglycerin plus flavored Chaihu Shugan San. The two groups were treated for 20 days. The clinical efficacy and the changes of plasma brain natriuretic peptide (BNP) before and after treatment were compared between the two groups. Results: The total effective rate was 96.0% in the observation group and 86.0% in the control group. There was significant difference between the two groups (P <0.05). After treatment, BNP levels in both groups were lower than those before treatment (P <0.05), BNP level in the observation group was lower than that in the control group (P <0.05). Conclusion: Based on the treatment of nitroglycerin tablets, the clinical efficacy of Modified Chaihu Shugan Powder in treating patients with coronary heart disease with blood stasis obstruction is better than that of Fufang Danshen tablets.