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目的分析研究原发性胆汁性肝硬化合并糖尿病的临床特征。方法原发性胆汁性肝硬化的患者180例,其中合并糖尿病的患者有30例,将这30例原发性胆汁性肝硬化合并糖尿病的患者命名为合并组,将其他的150例单纯原发性胆汁性肝硬化的患者命名为单纯组,回顾总结这两组患者的临床表现和并发症、病程以及年龄性别等因素,分析研究原发性胆汁性肝硬化合并糖尿病的临床特征。结果两组在性别上比较,差异有统计学意义(P<0.05);两组在年龄上比较,差异有统计学意义(P<0.05),合并组多集中在老年人。在乏力和下肢水肿方面比较差异有统计学意义(P<0.05),在纳差、腹胀、肝掌和黄疸上比较,差异无统计学意义(P>0.05);在腹水、消化道出血上、胸水上两组比较,差异有统计学意义(P<0.05)。结论原发性胆汁性肝硬化合并糖尿病的临床上的特征为:老年人的发病率高,乏力,下肢水肿的症状明显,容易并发腹水和胸水。在临床上为诊断和治疗提供指导的意义。
Objective To analyze the clinical features of primary biliary cirrhosis with diabetes. Methods 180 patients with primary biliary cirrhosis, including 30 patients with diabetes mellitus, 30 patients with primary biliary cirrhosis and diabetes mellitus were named the merger group, the other 150 cases of primary primary The patients with biliary cirrhosis were named simple group. The clinical manifestations, complication, course of disease and age, sex and other factors of these two groups were reviewed and summarized. The clinical features of primary biliary cirrhosis with diabetes were analyzed. Results There were significant differences in gender between the two groups (P <0.05). There was significant difference between the two groups in age (P <0.05). The combined group was more concentrated in the elderly. There were significant differences in fatigue and lower extremity edema (P <0.05), but there was no significant difference in anorexia, abdominal distension, liver and jaundice (P> 0.05); in ascites, gastrointestinal bleeding, Pleural effusion on the two groups, the difference was statistically significant (P <0.05). Conclusions The clinical features of primary biliary cirrhosis with diabetes are as follows: The incidence of the elderly is high and the symptoms of the lower extremities edema are obvious. It is easy to be complicated with ascites and pleural effusion. Provide clinical significance for diagnosis and treatment.