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重型再生障碍性贫血(再障)是肝炎的不常见并发症,晚近认为C型肝炎病毒(HCV)是输血后肝炎及伴或不伴有慢性肝病(包括肝癌)的散发性肝炎的主要病原。本文旨在了解再障患者中HCV的流行情况,以确定HCV是否导致肝炎后再障。重型再障118例,其中19例(16.1%)与肝炎有关。9例在发生再障前1～6月,有急性肝炎症状伴转氨酶升高;13例入院时转氨酶升高,6例正常。2例经肝活检组织学证实为急性肝炎。118例中61例(52%)为不明原因的重型再障,病前均无输血液制品或肝炎
Severe Aplastic Anemia (AA) is a rare complication of hepatitis and Hepatitis C virus (HCV) is lately considered to be the major causative agent of post-transfusion hepatitis and sporadic hepatitis with or without chronic liver disease including liver cancer. The purpose of this article is to understand the prevalence of HCV in patients with aplastic anemia and to determine if HCV causes post-hepatitis aplasia. 118 cases of severe aplastic anemia, of which 19 cases (16.1%) and hepatitis. In the 9 cases before the onset of aplastic anemia from January to June, acute hepatitis symptoms accompanied by elevated transaminases; 13 cases of elevated transaminases, 6 cases were normal. 2 cases confirmed by histological liver biopsy as acute hepatitis. Of the 118 patients, 61 (52%) had unexplained severe aplastic anemia without any transfusion of blood products or hepatitis