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临床资料表明 ,癫状态中选择性易损伤区为海马CA1区 ,为了解癫发生与海马CA1区损伤的关系 ,笔者通过戊四氮致大鼠模型研究海马CA1区超微结构改变。1 材料与方法清洁级近交系SD雄性大鼠 6只 [上海西普尔 必凯实验动物有限公司 ,许可证号 :Scxk(沪 ) 2 0 0 3 0 0 0 2 ],
Clinical data show that the selective vulnerable area in epileptic state is hippocampal CA1 area. To understand the relationship between epileptic area and damage of hippocampal CA1 area, we investigated the ultrastructural changes of hippocampal CA1 area by rat model of pentylenetetrazole. 1 Materials and methods Clean-grade SD male rats inbred 6 [Shanghai Purcell Experimental Animal Co., Ltd., license number: Scxk (Shanghai) 200003000],