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目的探讨干扰素联合电离子脉冲治疗尖锐湿疣的临床疗效。方法 48例尖锐湿疣患者,随机分为研究组与对照组,各24例。对照组采用电离子脉冲治疗,研究组采用干扰素联合电离子脉冲治疗。观察比较两组的复发率、痊愈率及不良反应发生率。结果治疗后研究组复发率为12.50%,明显优于对照组的41.66%,差异有统计学意义(P<0.05);研究组痊愈21例(87.50%),显著优于对照组的14例(58.33%),差异有统计学意义(P<0.05);两组不良反应经处理后均可耐受。结论对尖锐湿疣疾病患者采用干扰素联合电离子脉冲治疗方法临床疗效显著,且不良反应发生率低,值得临床推广应用。
Objective To explore the clinical efficacy of interferon combined with iontophoresis in the treatment of condyloma acuminatum. Methods 48 patients with condyloma acuminatum were randomly divided into study group and control group, with 24 cases in each group. The control group was treated with ionized pulse, while the study group was treated with interferon plus ionized pulse. The recurrence rate, cure rate and incidence of adverse reactions in the two groups were observed and compared. Results The recurrence rate of the study group was 12.50%, which was significantly better than that of the control group (41.66%), the difference was statistically significant (P <0.05); the study group was cured 21 cases (87.50%), significantly better than the control group of 14 cases 58.33%), the difference was statistically significant (P <0.05); two groups of adverse reactions can be tolerated after treatment. Conclusion The clinical efficacy of interferon combined with ionization pulse therapy in patients with condylomata acuminatum is significant, and the incidence of adverse reactions is low, which is worthy of clinical application.