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淀粉样变性是指在组织中出现淀粉样物(淀粉样蛋白)沉着的一种病变。它首先为Rokitan-sky(1842)所介绍,Virchow(1853)根据这种沉积物对碘有淀粉及纤维素样反应的特点,命名为淀粉样物,称这种病为淀粉样变性。淀粉样物是沉积在细胞外的无定形物,可出现在血管壁基底膜或小涎腺周围。从病理学角度认为它不是新生物而是变性的产物。光镜显示为玻璃样变:电镜下呈典型原纤维结构。组织化学成份为以半胱氨酸及酪氨酸为主体的氨基蛋白。这
Amyloidosis refers to the appearance of a disease in which the amyloid (amyloid) deposits in the tissue. It was first described by Rokitan-sky (1842). Virchow (1853) named amyloid on the basis of its starch and cellulose-like response to iodine and called the disease amyloidosis. Amyloid is an amorphous extracellular deposition that can occur around the basement membrane of the vascular wall or the small salivary gland. From a pathological point of view it is not a neoplasm but a denatured product. Light microscopy showed a glass-like transformation: a typical fibril structure under electron microscopy. Tissue chemical composition of cysteine and tyrosine as the main amino protein. This