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目的:调查我院苯二氮类药物(BDZ)的使用情况。方法:随机抽取宁夏精神卫生中心2007年5月～2008年5月的门诊西药处方5 499张,对其中1 799张含有苯二氮类药物的处方进行分析。并使用限定日剂量(DDD)和药物利用指数(DUI)为指标分析其使用情况。结果:含有苯二氮类药物的处方占总处方的32.72%,使用率最高的为阿普唑仑(占44.14%),其次为艾司唑仑、氯硝西泮、地西泮、劳拉西泮和三唑仑。其中,地西泮、劳拉西泮、三唑仑的DUI均小于1,阿普唑仑、艾司唑仑、氯硝西泮的DUI大于1。用药时间超过4周的处方高达27.85%,超过8周的处方为0.83%,最高处方天数为12周。结论:我院苯二氮类药物的使用不存在滥用倾向。
Objective: To investigate the use of benzodiazepines (BDZ) in our hospital. Methods: 5 499 prescriptions of outpatient western medicine were collected from Ningxia Mental Health Center from May 2007 to May 2008 at random, and 1 799 prescriptions containing benzodiazepines were analyzed. The use of defined daily dose (DDD) and drug use index (DUI) as an indicator of its use. Results: The prescriptions containing benzodiazepines accounted for 32.72% of the total prescriptions, the highest usage rate was alprazolam (44.14%), followed by eszolam, clonazepam, diazepam, Diazepam and triazolam. Among them, the DUI of diazepam, lorazepam and triazolam were all less than 1. The DUI of alprazolam, estazolam, and clonazepam was greater than 1. Prescriptions that took longer than 4 weeks were as high as 27.85%, those with more than 8 weeks were 0.83% and those with the highest prescriptions were 12 weeks. Conclusion: The abuse of benzodiazepines in our hospital does not exist.