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大量的流行病学证据表明幽门弯曲杆菌(CP)是球部溃疡(DU)的原因。但细菌如何引起 DU 仍属推测。本文报道 CP 阳性或阴性的 DU 病人的食物刺激的胃泌素释放和五肽胃泌素刺激的胃酸分泌,旨在阐明 CP 的发病学作用。方法 31例选用内镜检查诊断为 DU 的病例,无其他相关疾病,未做过胃或迷走神经手术,3天内无服用 H_2-受体拮抗剂,8周内未服用三钾二枸橼酸铋(DeNol)。均在胃窦部取活检2块,应用尿素酶法监
Numerous epidemiological evidences indicate that Campylobacter pylori (CP) is responsible for ulceration (DU). But how bacteria cause DU is still speculated. This paper reports the food-stimulated gastrin release and pentagastrin-stimulated gastric acid secretion in DU patients with CP-positive or -negative DU, aiming to elucidate the pathogenesis of CP. Methods Thirty-one cases with DU were diagnosed by endoscopy. There were no other related diseases, no gastric or vagotomy surgery, no H 2 -receptor antagonist within 3 days, no tripotassium citrate bismuth citrate DeNol). Take a biopsy in the antrum 2, the application of urease law