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细胞内钙是决定血管平滑肌细胞产生张力的重要因素.游离钙是调节血管平滑肌张力的所有神经体液因素产生作用的必须环节.在自发性高血压的大鼠观察到细胞内钙浓度增高,在原发性高血压患者的脂肪组织中也有类似发现.近来 Erne 等采用细胞内固定荧光染料 Quin-2,观察到临界和确诊的高血压患者血小板中游离钙浓度较血压正常者增
Intracellular calcium is an important factor that determines the tension of vascular smooth muscle cells.Free calcium is a necessary part of the regulation of all neurohumoral factors that regulate the vascular smooth muscle tone.It is observed in the spontaneously hypertensive rats that intracellular calcium concentration is increased, Similar findings have been found in adipose tissue of patients with hypertension, and Erne et al recently used Quin-2, a fluorescent dye that is intracellularly fixed, to observe increased levels of free calcium in platelets in critically ill and diagnosed hypertensives compared with normotensive subjects