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目的分析对液基细胞学诊断为非典型鳞状上皮细胞,不除外上皮内高度病变(ASC-H)和鳞状上皮高度病变(HSIL)的临床指导意义。方法将ASC-H及HSIL病例行阴道镜检查并取组织活检并对结果作对照分析。结果细胞学诊断为ASC-H的51例病例中,34例有组织学病理对照,其中10例慢性宫颈炎、3例CINⅠ、8例CINⅡ、11例CINⅢ、2例SCC,阳性检出率70.6%。68例HSIL病例中有46例组织学病理对照,其中1例CINⅠ、3例CINⅡ、33例CINⅢ、9例SCC,阳性检出率100.0%。结论宫颈细胞学结果为ASC-H有较高的CIN阳性预测价值,HSIL则高度提示有上皮内瘤变的存在,临床应予以极高度重视。
Objective To analyze the clinical significance of liquid-based cytological diagnosis of atypical squamous epithelium, non-excised intraepithelial lesion (ASC-H) and squamous cell carcinoma (HSIL). Methods ASC-H and HSIL cases colposcopy and biopsy taken and the results for control analysis. Results Among the 51 cases with cytological diagnosis of ASC-H, 34 cases had histopathological control, of which 10 cases had chronic cervicitis, 3 cases of CINⅠ, 8 cases of CINⅡ, 11 cases of CINⅢ and 2 cases of SCC. The positive detection rate was 70.6 %. 46 cases of HSIL 68 cases histological and histological control, including 1 CIN Ⅰ, 3 cases of CIN Ⅱ, 33 cases of CIN Ⅲ, 9 cases of SCC, the positive detection rate of 100.0%. Conclusions Cervical cytology results show that ASC-H has a high predictive value of CIN, HSIL is highly suggestive of intraepithelial neoplasia, which should be highly valued in clinic.