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氯丁二烯是工业合成氯丁橡胶和氯丁胶粘剂的单体,常温下为气体,易聚合。据文献报道,氯丁二烯的突出毒作用是肝脏损害、神经系统影响、脱发和指甲变色。近年来,人们注意到氯丁二烯的致癌、致突变、致畸作用。有关生殖危害的研究有的认为氯丁二烯具有生殖毒性和胚胎毒性。苏联学者甚至根据其生殖毒性建议重新修订空气中氯丁二烯的最高容许浓度。但也有的学者认为氯丁二烯无生殖毒性和胚胎毒性。本文就氯丁二烯对动物和人群的生殖危害研究概况作一介绍。
Chloroprene is a synthetic neoprene and neoprene industrial monomer, at room temperature as a gas, easy polymerization. It has been reported in the literature that the prominent toxic effects of chloroprene are liver damage, nervous system effects, hair loss and nail discoloration. In recent years, people have noticed the carcinogenic, mutagenic and teratogenic effects of chloroprene. Studies on reproductive harm have suggested that chloroprene has reproductive toxicity and embryotoxicity. Soviet academics have even revised the maximum allowable concentration of chloroprene in the air based on their reproductive toxicity recommendations. However, some scholars think that chloroprene has no reproductive toxicity and embryotoxicity. In this paper, chloroprene on animal and human reproductive harm research profile to make an introduction.