论文部分内容阅读
本研究旨在观察经鼻持续性气道正压(nCPAP)对未行机械通气的慢性阻塞性肺病(COPD)急性发作期合并急性呼吸衰竭患者的治疗作用。 材料与方法 对15例确诊为COPD发生急性呼衰而入院的勿须立即行气管插管的男性患者进行了实验.其平均年龄64±7(47～74)岁,FEV_125±8％,最大呼气流量(PEF)36±13％。受试者均符合下列条件:①入院时 PaCO_2>55mmHg或入院后1小时内下降>5mmHg;②严重的气道阻塞(FEV-1低于预计值的40％,FEV_1/FVC低于预计值的60％);③意识状态良好。除外睡眠呼吸暂停综合征、胸膜或胸壁病理异常伴
The aim of this study was to investigate the therapeutic effect of nasal continuous positive airway pressure (nCPAP) on patients with acute respiratory failure during acute exacerbation of chronic obstructive pulmonary disease (COPD) without mechanical ventilation. MATERIALS AND METHODS: Fifteen men admitted to hospital who did not require immediate tracheal intubation admitted to hospital for acute respiratory failure who had been diagnosed with COPD had an average age of 64 ± 7 (47-74 years) and FEV 125 ± 8% Gas flow (PEF) 36 ± 13%. The subjects met the following criteria: ① admission PaCO_2> 55mmHg or within 1h after admission decreased> 5mmHg; ② severe airway obstruction (FEV-1 less than 40% of the expected value, FEV_1 / FVC lower than expected 60%); ③ Consciousness is good. Except for sleep apnea syndrome, abnormal pleural or chest wall pathology