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目的:探讨中枢神经系统炎症性疾病患者的脑脊液激光光谱特性。方法:用氩激光对50例中枢神经系统疾病的病人脑脊液作了实验研究。对患病组与正常组脑脊液进行光偏振和荧光物理特性测量,以及脑炎患者脑脊液治疗前后的光谱测量。结果:病人脑脊液的分子对称性低于正常脑脊液,但荧光强度明显偏高;在氩激光照射下,正常脑脊液荧光强度随时间延长变化较小,病态脑脊液荧光强度变化较大。治疗前后脑炎患者 Ram an 带强度发生了明显变化。结论:用激光光谱检测脑脊液在诊断中枢神经系统炎症性疾病方面,有着其它方法难以比拟的临床优点。为临床提供了一项新的物理学诊断方法。
Objective: To investigate cerebrospinal fluid laser spectroscopy in patients with central nervous system inflammatory diseases. Methods: Fifty patients with central nervous system diseases were treated with argon laser. Measurement of light polarization and fluorescence properties of cerebrospinal fluid in diseased and normal subjects, and spectroscopic measurements before and after cerebrospinal fluid treatment in patients with encephalitis. Results: The molecular symmetry of cerebrospinal fluid of patients was lower than that of normal cerebrospinal fluid, but the fluorescence intensity was obviously higher. Under argon laser irradiation, the fluorescence intensity of normal cerebrospinal fluid changed little with time, and the fluorescence intensity of pathological cerebrospinal fluid changed greatly. The intensity of Ram an band in patients with encephalitis before and after treatment changed obviously. CONCLUSIONS: Laser spectroscopy for the detection of cerebrospinal fluid in the diagnosis of central nervous system inflammatory diseases has clinical advantages that are unmatched by other methods. For clinical clinical diagnosis provides a new method.