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目的:观察逍遥散加减联合甘利欣降低慢性乙型肝炎大学生转氨酶的效果。方法:将78例患者随机分为治疗组50例予逍遥散加减联合甘利欣治疗,对照组28例单独予甘利欣治疗。结果:2组治疗前后中医证候积分分别比较,差异均有非常显著性意义(P<0.01);治疗后治疗组证候积分明显低于对照组(P<0.05)。2治疗前后积分差值比较,差异有显著性意义(P<0.05)。2组中医证候疗效总有效率比较,差异有显著性意义(P<0.05)。2组丙氨酸氨基转移酶(ALT)总有效率比较,差异有显著性意义(P<0.05)。结论:逍遥散加减联合甘利欣不仅能有效地降低ALT,而且能明显改善患者的不适,适合用于慢性乙型肝炎大学生的降酶治疗。
Objective: To observe the effect of Xiaoyao San combined with Gan Lixin on reducing transaminase of chronic hepatitis B college students. Methods: Seventy-eight patients were randomly divided into treatment group (n = 50) treated with Xiaoyao San plus Gan Lixin (n = 28) and control group (n = 28) treated with Gan Lixin alone. Results: Before and after treatment, TCM syndrome scores were significantly different (P <0.01). After treatment, the syndrome scores of the treatment group were significantly lower than those of the control group (P <0.05). 2 points before and after treatment difference, the difference was significant (P <0.05). The total effective rate of TCM syndromes in the two groups was significantly different (P <0.05). There was significant difference between the two groups in the total effective rate of alanine aminotransferase (ALT) (P <0.05). Conclusion: Xiaoyao San combined with Gan Lixin not only can effectively reduce ALT, but also can significantly improve the patient’s discomfort, suitable for college students with chronic hepatitis B enzyme treatment.