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为评价头颈部鳞癌术后复发患者行姑息放疗的疗效及其影响因素，对１９８８年７月至１９９６年２月在我科接受姑息放疗的１０６例患者的资料行回顾性分析。结果：放疗后ＣＲ２２．６％（２４／１０６），ＰＲ３８．７％（４１／１０６），ＮＲ３８．７％（４１／１０６）；总有效率为６１．３％（６５／１０６）；放疗后挽救性手术成功率为４／９；疗后６３．２％（６７／１０６）的患者Ｋａｒｎｏｆｓｋｙ得分上升，症状减轻，生存质量提高；１、２、３年生存率分别为５４．７％（５８／１０６）、２１．７％（２３／１０６）和５．７％（６／１０６）；远处转移率２９．２％（３１／１０６），放疗并发症１０．４％（１１／１０６）。结论：姑息放疗是晚期头颈部鳞癌术后复发患者一种较好的治疗选择；为了提高疗效，放射剂量应尽可能高于５０Ｇｙ，采用超分割连续放疗技术和避免分段。
To evaluate the efficacy and influencing factors of palliative radiotherapy in patients with head and neck squamous cell carcinoma after recurrence, we retrospectively analyzed the data of 106 patients who received palliative radiotherapy in our department from July 1988 to February 1996. Results: After radiotherapy, CR was 22.6% (24/106), PR was 38.7% (41/106), and NR was 38.7% (41/106); the total effective rate was 61.3% (65/106); after radiotherapy The success rate of salvage surgery was 4/9; after treatment, 63.2% (67/106) patients had Karnofsky scores increased, symptoms were relieved, and the quality of life was improved; the 1-, 2-, and 3-year survival rates were 54.7% (58). /106), 21.7% (23/106) and 5.7% (6/106); distant metastasis rate 29.2% (31/106), radiotherapy complications 10.4% (11/106) . CONCLUSIONS: Palliative radiotherapy is a good treatment option for patients with advanced head and neck squamous cell carcinoma after recurrence. To increase the efficacy, the radiation dose should be higher than 50 Gy as far as possible, and ultra-segmented continuous radiotherapy should be used to avoid segmentation.