论文部分内容阅读
临床和实验证明,单细胞生物物理特性和人类疾病之间有着千丝万缕的联系。从二十世纪六十年代起,人们就开始对这一自然规律展开研究,期望从中揭开一些疑难杂症的神秘面纱。然而,工欲善其事,必先利其器。解决上述难题,研究人员首先面临的就是开发出具有高通量、鲁棒性和易于操作的单细胞生物物理特性测量工具这一挑战。细胞是生物体的基本功能单元,它通过内部化学、物理方式维持和感觉外部生理环境。独一无二的生物化学和生物物理特性使细胞能够实现特殊功能,并且适应外部环境。细胞的生理变化是伴随着自身一系列化学物理方面的改变和
Clinical and experimental evidence shows that the single-cell biophysical properties and human diseases are inextricably linked. Since the 1960s, people started to study this law of nature and hoped to uncover the mystery of some incurable diseases. However, workers want good things, must first sharpen their tools. To solve these problems, researchers first faced the challenge of developing a single-cell biophysical properties measurement tool with high throughput, robustness and ease of operation. Cells are the basic functional units of an organism, which maintain and feel the external physiological environment through internal chemistry and physics. Unique biochemical and biophysical properties enable cells to perform specific functions and adapt to the external environment. Physiological changes in cells are accompanied by a series of chemical and physical changes in themselves