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目的:探讨联合用药治疗方式对老年人消化性溃疡急性上消化道出血的治疗效果。方法:选择在我院接受治疗的36例老年消化性溃疡急性上消化道出血患者作为研究对象,将其随机分为对照组与观察组,每组18例。其中对照组患者单独应用奥美拉唑治疗,观察组患者联合应用血凝酶、奥曲肽以及奥美拉唑治疗。比较两组患者的治疗效果以及并发症发生情况。结果:观察组患者止血效果明显优于对照组(P<0.05);患者治疗的主要不良反应为轻微的腹胀、恶心等,经处理后可消除,两组比较无明显差异(P>005)。结论:对老年消化性溃疡急性上消化道出血采用联合用药方式进行抑制胃酸和止血的治疗效果明显,同时不会增加不良反应对老年患者心血管系统的影响,安全性高,值得临床推广应用。
Objective: To explore the therapeutic effect of combination therapy on acute upper gastrointestinal bleeding of peptic ulcer in the elderly. Methods: 36 elderly patients with peptic ulcer acute upper gastrointestinal bleeding who were treated in our hospital were selected as the study subjects, and randomly divided into control group and observation group, with 18 cases in each group. The control group of patients treated with omeprazole alone, the observation group patients combined hemagglutination enzyme, octreotide and omeprazole treatment. The curative effect and complication of the two groups were compared. Results: The hemostatic effect of the observation group was better than that of the control group (P <0.05). The main side effects of the treatment were slight bloating and nausea, which could be eliminated after treatment. There was no significant difference between the two groups (P> 0.05). Conclusion: The treatment of acute upper gastrointestinal bleeding peptic ulcer with combination therapy for gastric acid suppression and hemostasis is obvious, and will not increase the adverse effects on cardiovascular system in elderly patients with high safety, which is worthy of clinical application.