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目的:分析维生素K1、酚磺乙胺联合应用治疗新生儿凝血功能障碍的临床疗效。方法:选取我院2012年1月-2013年11月收治的90例新生儿凝血功能障碍患儿为研究对象,将其随机分成两组,对照组44例患儿给予常规治疗,观察组46例患儿在常规治疗基础上给予维生素K1、酚磺乙胺联合治疗,观察两组临床疗效。结果:观察组患儿各项指标如凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)、凝血酶时间(TT)及血小板计数等改善情况显著优于对照组,差异显著具有统计学意义(P<0.05)。结论:维生素K1、酚磺乙胺联合治疗新生儿凝血功能障碍的临床疗效较显著,其能有效改善患儿各项指标,值得应用。
OBJECTIVE: To analyze the clinical effect of vitamin K1 combined with phenylethanolamine in the treatment of neonatal coagulation disorders. Methods: Ninety cases of neonates with coagulopathy admitted in our hospital from January 2012 to November 2013 were selected and randomly divided into two groups. Forty-four children in the control group were given routine treatment. The observation group included 46 cases Children on the basis of conventional treatment given vitamin K1, phenylethyl sulfonamide combination therapy, the clinical efficacy of the two groups were observed. Results: The improvement of various indexes in the observation group such as prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB), thrombin time (TT) and platelet count were significantly better Control group, the difference was statistically significant (P <0.05). Conclusion: The clinical efficacy of vitamin K1 and ethanesulfonamide in the treatment of neonatal coagulation dysfunction is significant. It can effectively improve the indexes of children and is worthy of application.