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转移因子是白细胞透析液中的一种具有免疫增强和调节作用的活性物质.它能特异地转移细胞介导免疫反应.临床上转移因子已用于治疗恶性肿瘤,并取得了不同程度的效果.Krish等报道用转移因子治疗术后肺癌患者,发现两年存活率在治疗组(78%)和对照组(46%)之间有明显差异;特异性转移因子治疗恶性肿瘤国内外报道甚少.第四军医大学曾用肺癌标本制备抗原免疫山羊,制成特异性转移因子治疗50例肺癌患者,结果不仅证明该转移因子有抗原特异性,而且使病人的免疫力有所提高.本文对食管癌特异性转移因子的制备及其活性进行了研究,报告如下:
Transfer factor is an active substance in leukocyte dialysate with immune enhancement and regulation. It can specifically transfer cell-mediated immune response. Clinically, transfer factor has been used to treat malignant tumors, and has achieved varying degrees of effect. Krish et al. reported that the use of transfer factor in the treatment of postoperative lung cancer patients found that the two-year survival rate was significantly different between the treatment group (78%) and the control group (46%); the specific transfer factor treatment of malignant tumors is rarely reported at home and abroad. The Fourth Military Medical University had used lung specimens to prepare antigens to immunize goats and made specific transfer factors to treat 50 patients with lung cancer. The results not only proved that the transfer factor has antigen specificity, but also improved the patient’s immunity. This article is about esophageal cancer. The preparation and activity of specific transfer factors were studied and reported as follows: