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目的:探讨小剂量米非司酮治疗子宫肌瘤的临床效果及对其不良反应的影响。方法:选取我院2012年5月~2013年5月收治的45例子宫肌瘤患者作为临床研究对象,将其随机分为23例观察组和22例对照组,对照组患者给予常规剂量米非司酮治疗,观察组患者给予小剂量米非司酮进行治疗,对其疗效及不良反应进行观察。结果:两组患者的子宫体积和子宫肌瘤体积改善情况对比差异不显著(P>0.05);但观察组患者的不良反应率明显低于对照组(P<0.05)。结论:对子宫肌瘤患者采用小剂量米非司酮进行治疗,可在有效保证治疗效果的基础上,明显减轻其不良反应等副作用,可明显改善患者状况,疗效更为明显,值得临床推广应用。
Objective: To investigate the clinical effect of low-dose mifepristone in the treatment of uterine fibroids and its adverse reaction. Methods: Forty-five patients with uterine fibroids admitted from May 2012 to May 2013 in our hospital were selected as clinical study subjects and randomly divided into observation group (23 cases) and control group (22 cases). Patients in control group Cholesterol treatment, observation group patients given low-dose mifepristone for treatment, its efficacy and adverse reactions were observed. Results: There was no significant difference in uterine volume and uterine myoma volume between the two groups (P> 0.05). However, the adverse reaction rate in the observation group was significantly lower than that in the control group (P <0.05). Conclusion: The treatment of uterine fibroids with low dose of mifepristone can effectively reduce the side effects of adverse reactions, which can significantly improve the patient’s condition, the effect is more obvious, it is worthy of clinical application .