论文部分内容阅读
目的研究临床标本检出产超广谱β-内酰胺酶大肠埃希菌的耐药特性,为临床科学选药提供依据。方法采用临床标本检测和细菌鉴定技术,对某医院临床送检标本病原学检测和细菌鉴定结果及耐药性进行调查与分析。结果分离自感染患者痰液和尿液中的产超广谱β-内酰胺酶大肠埃希菌对临床常用抗菌药物普遍耐药;对头孢哌酮、头孢呋辛钠和磷霉素的耐药率均为100%;仅对亚胺培南和美罗培南比较敏感。结论分离自不同标本中的产超广谱β-内酰胺酶大肠埃希菌对多数抗菌药耐药,仅对极少数抗菌药物比较敏感,提示临床要根据药敏试验结果选择抗菌药物。
Objective To study the drug resistance characteristics of extended-spectrum β-lactamase-producing Escherichia coli (ESBL) in clinical specimens and to provide the basis for selection of clinical medicine. Methods The clinical specimens and bacterial identification techniques were used to investigate and analyze the pathogenicity, bacterial identification and drug resistance of clinical specimens from a hospital. Results The isolates of Escherichia coli producing extended-spectrum β-lactamases in sputum and urine from infected patients were generally resistant to commonly used antibiotics in clinical trials. Drug resistance to cefoperazone, cefuroxime sodium and fosfomycin Rates were 100%; only sensitive to imipenem and meropenem. Conclusion ESBLs-producing Escherichia coli isolated from different samples are resistant to most antibacterials and sensitive to very few antibacterials, suggesting that antibacterials should be selected according to the susceptibility test results.