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为了寻求常温下完全阻断肝血流的最大时限,作者选用56只健康家兔进行了实验研究。 实验共分5组,常温下阻断肝门时间按组序分别为30、45、60,90、120分钟,并观察动物神态、饮食、生化指标、病理变化等,实验观察结果:肝门阻断术后各实验组的兔先后可出现AKP、SGPT,LDH等变化,高峰值一般出现在第一天,在生存兔中,这几种酶的变化程度与肝血流阻断时间有关;术后20天处死兔病理检查,各实验组可见汇管区炎性细胞浸润;术后15小时内死亡的13只兔中有肺、肾和小肠病理改变,90、120分钟组均有明显组织形态学改变。文章中作者就家兔对常温下阻断肝门最大耐受时限、肝门阻断术
In order to find the maximum time limit for completely blocking hepatic blood flow at room temperature, the authors selected 56 healthy rabbits for experimental study. The experiment was divided into five groups. The time of blocking the hepatic portal at room temperature was 30, 45, 60, 90 and 120 minutes respectively, and the animals’ demeanor, diet, biochemical indexes and pathological changes were observed. The rabbits in each experimental group after AKA, AKP, SGPT, LDH and other changes after the operation were severed. The peak appeared on the first day. In the surviving rabbits, the changes of these enzymes were related to the time of hepatic blood flow blocking. Rabbit rabbits were sacrificed 20 days after the pathological examination, the experimental group of inflammatory cells can be seen in the portal area infiltration; within 15 hours after the death of 13 rabbits in the lung, kidney and small intestine pathological changes, 90,120 minutes were significantly histological change. The author of the article on rabbits at room temperature to block the most tolerable portal hypertension time limit, hilar block