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[目的]探讨原发性肺癌骨转移的临床相关因素。[方法]34例原发性肺癌骨转移病例入组。骨转移率用Kaplan-Meier法计算,单因素分析用Logrank法,多因素用Cox回归模型。[结果]从肺癌确诊开始到出现骨转移的中位时间为8个月。病理类型及淋巴结分期可影响骨转移发生率。[结论]病理为腺鳞癌、淋巴结受累程度高的肺癌患者应进行积极的随访(尤其在确诊肺癌后的第一年)。
[Objective] To explore the clinical factors related to bone metastasis of primary lung cancer. [Methods] 34 cases of primary lung cancer with bone metastases were enrolled. Bone metastasis was calculated by Kaplan-Meier method, Logrank method for univariate analysis and Cox regression model for multiple factors. [Results] The median time from the start of lung cancer diagnosis to the occurrence of bone metastasis was 8 months. Pathological types and lymph node staging can affect the incidence of bone metastases. [Conclusion] Patients with lung cancer whose pathology is adenosquamous carcinoma and lymph node involvement should be followed up actively (especially in the first year after diagnosis of lung cancer).