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目的:了解国际移动医疗应用程序研究的发展现状和时下研究热点，以期为国内开展移动医疗应用程序研究提供参考。方法:系统检索2009—2019年收录在Web of Science核心合集数据库的英文文献，文献类型为Article，利用CiteSpace （V.5.6.R2版本）软件对国际移动医疗应用程序领域的研究机构、来源期刊、被引文献、关键词等进行可视化分析。结果:共纳入4 705篇文献，国际移动医疗应用程序研究呈持续性增加趋势；发文量最多的机构和期刊分别是华盛顿大学和《JMIR Mhealth and Uhealth》；通过相关文献的关键词共现聚类得出移动医疗应用程序可行性研究、移动医疗应用程序干预性研究、疾病管理和自我保健、移动医疗应用程序评价4个研究热点。结论:为推动我国移动医疗应用程序研究的发展，建议未来研究人员应及时关注国际权威机构、期刊的研究成果，借鉴国际移动医疗应用程序研究知识基础，探索符合我国国情的应用程序研发之路。同时应规范设计研究方案，开展高质量干预性研究，并尽快构建我国移动医疗应用程序评价体系。“,”Objective:To explore the development status and research hotspots of international mobile medical application, so as to provide references for domestic research on mobile medical applications.Methods:We systematically searched English documents included in the Web of Science core database from 2009 to 2019, and the document type was the article. CiteSpace (V.5.6.R2 version) software was used to visually analyze research institutions, source journals, cited documents and keywords of international mobile medical applications.Results:A total of 4 705 documents were included. Research on international mobile medical applications continued to increase. The institution and journal with the most publications were the University of Washington and n JMIR Mhealth and Uhealth respectively. Through the keyword co-occurrence clustering of related literature, four research hotspots were obtained: the feasibility study of mobile medical applications, the intervention research of mobile medical applications, disease management and self-care, and the evaluation of mobile medical applications.n Conclusions:In order to promote the development of mobile medical application in China, it is recommended that future researchers should pay attention to the research result of international authoritative institutions and journals in a timely manner, learn from the knowledge base of international mobile medical application research, and explore the road of application development in line with my country's national conditions.At the same time, it is necessary to standardize the design of research programs, carry out high-quality intervention research, and build my country's mobile medical application evaluation system as soon as possible.