依那普利对无症状或症状轻微的因二尖瓣脱垂或风心病继发二尖瓣反流患者的左心室直径和运动耐量的影响

• 作 者: Sampaio R. O. Grinberg M. Leite J. J. 姜朝晖
• 机 构: Department of Valvular Heart Disease Heart Institute(InCor) University of So Paulo Medical School,
• 出 处: 世界核心医学期刊文摘(心脏病学分册)
• 发表日期: 2005年11期
• 关键词: 二尖瓣脱垂 依那普利 风心病 运动耐量 无症状 二尖瓣反流 左心室 直径 收缩功能 症状

The effects of 12 months of therapy were evaluated in 47 mildly symptomatic patients with moderate to severe mitral valve regurgitation; 26 patients received enalapril and 21 received a placebo. Enalapril was associated with a significant reduction in left ventricular diameter and mitral regurgitation volume, with no evidence of change in systolic function indexes. However, enalapril did not hinder progressive aerobic impairment to effort.

The effects of 12 months of therapy were evaluated in 47 mildly symptomatic patients with moderate to severe mitral valve regurgitation; 26 patients received enalapril and 21 received a placebo. Enalapril was associated with a significant reduction in left ventricular diameter and mitral regurgitation volume, with no evidence of change in systolic function indexes. However, enalapril did not hinder progressive aerobic impairment to effort.