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目的分析比较糖尿病组与非糖尿病组颈内动脉重度狭窄或闭塞后侧支循环情况与缺血事件的随访观察。方法取自2014年1月~2014年12月在我院经颈部血管彩超(DUS)确认的单侧颈内动脉重度狭窄(≥70%)或闭塞的患者77例,设立糖尿病组(37例)和非糖尿病组(40例),行颅多普勒超声(TCD)判断颅内侧支循环,比较分析两组侧支开放数目。结果卡方检验分析两组侧支循环开放数目,非糖尿病组2个侧支开放率高于糖尿病组(P<0.05);侧支开放种类两组比较无显著差异(P>0.05);随访1年发现非糖尿病组中5例发生TIA,糖尿病组12例,差异有统计学意义(P<0.05)。结论糖尿病可能阻碍狭窄后颅内侧支循环开放,侧支血管的发生受损在糖尿病患者中风的发病机制中可能是另一个重要因素。
Objective To analyze the follow-up of collateral circulation and ischemic events after severe stenosis or occlusion of carotid artery in diabetic and non-diabetic patients. Methods Totally 77 patients with severe unilateral carotid artery stenosis (≥70%) or occlusion confirmed by cervical ultrasonography (DUS) in our hospital from January 2014 to December 2014 were enrolled in this study. Diabetic patients (37 ) And non-diabetic group (40 cases). The intracranial branches of the brain were examined by CTA and the numbers of collaterals were compared. Results The chi-square test showed that the number of open collateral circulation in both groups was higher than that in the non-diabetic group (P <0.05). There was no significant difference between the two groups (P> 0.05) In the non-diabetic group, 5 cases were found to have TIA and 12 cases with diabetes mellitus, the difference was statistically significant (P <0.05). Conclusion Diabetes mellitus may hinder the opening of intracranial collateral circulation after stenosis. The impaired collateral vessels may be another important factor in the pathogenesis of stroke in diabetic patients.