论文部分内容阅读
Graves甲状腺毒症常并发慢性皮肤粘蛋白的浸润,特别是胫前(胫前粘液性水肿)。皮肤粘液性水肿虽可外用或病损内注射皮质类固醇治疗,但常无效。作者报告1例胫前粘液性水肿用PUVA治疗获得成功。患者女性,28岁,8个月来坐立不安、体重减轻、多汗、双眼球突出、双胫前发生粉红色坚实结节和斑块,其上毛孔口扩大。根据临床及化验检查确诊为Graves甲状腺毒症,伴发胫前粘液性水肿。因用甲状腺素和甲亢平治疗18个月无效,而行甲状腺次全切除。此后,在甲状腺素维持治疗后保持甲状腺功能正常。6个月后胫前皮损病理检查显示,真皮
Graves thyrotoxicosis is often associated with chronic mucocutaneous infiltration, particularly anterior tibial (tibialis anterior myxedema). Mucous edema may be topical or intra-corticosteroid injection treatment, but often ineffective. The authors report that one case of anterior tibial myxedema was successfully treated with PUVA. Female, 28 years old, restless for 8 months, lost weight, sweating, prominent both eyes, pink solid nodules and plaques in front of the double tibia, and enlarged upper oral orifice. According to clinical and laboratory tests confirmed Graves thyrotoxicosis, associated with anterior tibial myxedema. Due to thyroid hormone and hyperthyroidism treatment of 18 months invalid, while the line subtotal thyroidectomy. Since then, thyroid function remains normal after thyroxine maintenance treatment. 6 months after the anterior tibial lesions pathological examination showed that the dermis