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目的 通过时相法心 /肝比值的测定 ,对肝硬化导致的肝门脉高压、门静脉分流以及肝脾功能进行综合判断 ;方法 放射性心肌灌注显像剂99mTc MIBI经直肠给药 ,通过门脉分流回流入体循环 ,使不应显像的心肌显像 ;通过计算心 /肝 (H/L)比值 ,对肝硬化程度进行判断。结果 正常组与肝炎、肝硬化组时相分时相心 /肝比值有显著性差异 (t=2 2 14,P <0 0 5) ;肝硬化组早期与肝炎组H/L比值无意义外 ,其余各组分时相均有显著性差异 (t=3 0 0 3,P <0 0 0 1)。结论 时相法心 /肝比值对肝炎、肝硬化所造成的肝功能减低、门静脉分流和门静脉回流的诊断有显著的意义 ,是一项比较灵敏而特异的指标。
Objective To determine the hepatic portal hypertension, portal vein shunt and hepatic and splenic functions induced by cirrhosis through the determination of the phase-to-phase cardiac / hepatic ratio. Methods The radioactive myocardial perfusion imaging agent 99mTc MIBI was administered rectally via portal vein shunt Back into the systemic circulation, myocardial imaging should not be imaging; through the calculation of heart / liver (H / L) ratio, to determine the degree of cirrhosis. Results There was a significant difference in heart / liver ratio between normal group and cirrhosis group (t = 2 2 14, P <0 05). There was no significant difference between H / L ratio in early cirrhosis group and hepatitis group , The remaining components of the time phase were significantly different (t = 3 0 0 3, P <0 0 0 1). Conclusions The phase-to-phase ratio of cardiac / hepatic ratio has significant significance for the diagnosis of hepatic inflammation and liver cirrhosis caused by liver cirrhosis, portal vein shunt and portal venous return. It is a sensitive and specific indicator.