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目的探讨中医辅助治疗早期肝硬化的临床效果。方法 130例早期肝硬化患者,随机分为观察组和对照组,各65例。对照组患者给予常规西药治疗,观察组在对照组基础上加用中药治疗。对比两组治疗效果。结果观察组患者的谷丙转氨酶(ALT)、谷草转氨酶(AST)、总胆红素(TBil)和白蛋白(ALB)改善程度均显著优于对照组,差异具有统计学意义(P<0.01)。观察组患者的透明质酸(HA)、Ⅲ型前胶原(PCⅢ)、层粘蛋白(LN)以及Ⅳ型胶原(Ⅳ-C)改善程度均显著优于对照组,差异具有统计学意义(P<0.01)。结论以活血化瘀为理念的中药辅助治疗早期肝硬化,对于提高治疗效果具有积极意义,值得临床推广。
Objective To explore the clinical effect of adjuvant therapy of TCM on early cirrhosis. Methods 130 cases of early cirrhosis patients were randomly divided into observation group and control group, 65 cases each. Patients in the control group were treated with conventional western medicine. The observation group was treated with traditional Chinese medicine on the basis of the control group. Compare the two groups treatment effect. Results The improvement rate of ALT, TBil, ALB in the observation group was significantly better than that in the control group (P <0.01) . The improvement of hyaluronic acid (HA), PC Ⅲ, laminin (LN) and type Ⅳ collagen (Ⅳ-C) in the observation group was significantly better than that in the control group (P <0.01). Conclusion The treatment of early cirrhosis with traditional Chinese medicine based on the concept of activating blood circulation and removing blood stasis has positive significance for improving the therapeutic effect and is worthy of clinical promotion.