Proteolysis targeting chimera technology:a novel strategy for treating diseases of the central nervo

• 作 者: Ke Ma Xiao-Xiao Han Xiao-Ming
• 机 构: KeyLaboratoryofNeuroregenerationofJiangsuandMinistryofEducation,CollegeofLifeScience
• 出 处: 中国神经再生研究:英文版
• 发表日期: 2021年10期
• 关键词: Alzheimer’s disease disease treatment drug development Huntington’s disease prot
• 基金项目: This work was supported by the National Natural Science Foundation of China,No.81870975(to SLZ),the Nantong Science and Technology Innovation Program,China,No.JC2019028(to XMY).

Neurological diseases such as stroke,Alzheimer’s disease,Parkinson’s disease,and Huntington’s disease are among the intractable diseases for which appropriate drugs and treatments are lacking.Proteolysis targeting chimera(PROTAC)technology is a novel stra