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远在1934年Wade就提出结核样型麻风过渡到瘤型的轉变形式与混合型存在的可能性。此后Lowe、Kyrle、Gane等均曾論及这种中间状态的情况。1940年Wade和Rodriguez首先提出“界綫性结核样麻风”的名称。1952年世界卫生组织麻风病专门委员会将这类麻风定名为“界綫性(Borderline)麻风”,并将其列为麻风病的第四种形态。1953年第六次国际麻风会议上将这类麻风病定名为“界綫种(Borderline Group),并将“双形(Dimorphous)”一词列为界綫种麻风病的同义词,同时提出了界綫种麻风的定义。
As far back as 1934, Wade proposed the possibility of a transition from a lepromatous form of tuberculosis to a transition from a neoplastic form to a mixed form. Since then, Lowe, Kyrle, Gane, etc. have discussed this intermediate state. In 1940 Wade and Rodriguez first proposed the name “borderline tuberculosis-like leprosy.” In 1952, the Leprosy Commission of the World Health Organization designated such leprosy as “borderline leprosy” and listed it as the fourth form of leprosy. The 6th International Conference on Leprosy called this type of leprosy “Borderline Group” in 1953 and listed the term “Dimorphous” as synonymous with leprosy at the borderline, and at the same time raised the line of leprosy Definition.