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目的:探讨T-SPOT.TB试验在结核性脑膜炎的诊断与鉴别诊断的意义。方法:就我院2012年1月至2013年6月收治的脑膜炎患者99例,实验组给予患者T-SPOT.TB检验,对照组给予传统PPD试验,分析T-SPOT.TB检验方法在诊断结核性脑膜炎中的意义。结果:实验组通过T-SPOT.TB法对病例血清学检测阳性率的比较,p值<0.01,具有统计学意义。通过皮试法(TST法)进行结核菌素(PPD)实验对患者测试结果阳性率的比较得出的结果P值>0.05,不具有统计学意义。结论:T-SPOT.TB试验较传统PPD试验比较,其阳性结果判定可以作为早期辅助诊断结核性脑膜炎的依据。
Objective: To investigate the significance of T-SPOT.TB test in the diagnosis and differential diagnosis of tuberculous meningitis. Methods: Ninety-nine patients with meningitis were admitted to our hospital from January 2012 to June 2013. The patients in the experimental group were given T-SPOT.TB test, the control group were given the traditional PPD test, and the T-SPOT.TB test was used in the diagnosis The significance of tuberculous meningitis. Results: The positive rate of serological test in the experimental group by T-SPOT.TB method was statistically significant (p <0.01). By skin test (TST method) for tuberculin (PPD) test results of the positive rate of the patient test results obtained P value> 0.05, not statistically significant. Conclusion: T-SPOT.TB test compared with the traditional PPD test, the positive result can be used as an early diagnosis of tuberculosis meningitis basis.