论文部分内容阅读
在周期表上104种元素中,约80种为金属或类金属,其中至少有20种金属对人有毒性,但已知对人有致癌性的金属则为少数。近年来由于职业性肿瘤的研究受到广泛注意,而金属的工业用途甚广,接触人数众多,在环境中存留时间较长,因此金属致癌问题的研究也日益受到重视。目前评价化学物质的致癌性有三类方法:流行病学调查、整体动物实验、与体外致突变试验。依靠这三类方法,国际癌症研究机构
Of the 104 elements in the periodic table, about 80 are metals or metalloids, at least 20 of which are toxic to humans, but only a few are known to be carcinogenic to humans. In recent years, due to occupational cancer research has received widespread attention, and the metal has a wide range of industrial uses, exposure to a large number of people living in the environment for a long time, so the issue of metal carcinogenesis is also increasingly attention. There are currently three types of methods for assessing the carcinogenicity of chemical substances: epidemiological investigations, whole animal experiments, and in vitro mutagenicity tests. Relying on these three approaches, IARC