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众所周知HBV是一非杀伤细胞性病毒,因而机体的免疫反应乃是造成肝细胞损伤的主要原因。近年来在乙型肝炎病人免疫机理的研究中,对于HBcAg作为杀伤性T细胞攻击的靶抗原问题有了新的认识,对LSP、抗-LSP介导的ADCC作用在乙肝病人肝细胞损伤中的地位也给予肯定。在研究中还发现虽然一些非特异性淋巴细胞在急、慢性乙型肝炎时其功能低下,但是仍然有病毒特异的淋巴细胞和肝细胞膜自身抗原特异性淋巴细胞存在,说明机体的免疫反应是受到免疫调节系统控制
It is well-known that HBV is a non-killer cell virus, and thus the body’s immune response is the main cause of liver cell damage. In recent years, in the study of the immune mechanism of hepatitis B patients, we have got a new understanding of HBcAg as a target antigens attacked by killer T cells. The effects of LSP and anti-LSP mediated ADCC on hepatocyte injury in hepatitis B patients Status is also affirmed. In the study also found that although some nonspecific lymphocytes in acute and chronic hepatitis B, their dysfunction, but there are still virus-specific lymphocytes and liver cell membrane antigen-specific lymphocyte existence, indicating that the body’s immune response is immune Adjust system control