重症蝎子刺伤后的胃肠反应

来源 :世界核心医学期刊文摘(胃肠病学分册) | 被引量 : 0次 | 上传用户:whxust
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Objectives-To evaluate the type and incidence of gastrointestinal manifestations secondary to scorpion envenomation and their prognostic significance. Patients and methods-All patients admitted to our ICU for scorpion envenomation were included in this retrospective chart review of a 13-year period (1990 -2002). Results-During the study period, 951 patients were admitted for scorpion envenomation and 72 (7.6%) died. Ages ranged from 0.5 to 90 years with a mean of 14.7 ±17.4 years. Gastrointestinal symptoms were present in 700 patients (73.6%): nausea in 24 (2.5%), vomiting in 687 (72.2%) and diarrhea in 41 patients (4.3 %). At univariate analysis, the presence of diarrhea was associated with a fatal outcome (P < 0.05). Diarrhea was also correlated with other indicators of severe envenomation and poor prognosis: respiratory failure (P = 0.01), neurological failure (P < 0.0001), liver failure (P < 0.0001) and low blood pressure requiring catecholamine support (P = 0.02). The multivariate analysis showed that young age (age less than 5 years), fever > 38.5°C, neurological failure and pulmonary edema were independent factors of severity. Digestive disorders were more frequent in children and in this subgroup diarrhea appeared to be associated with poor outcome. In a subset of patients for whom data were available, fatal cases demonstrated significantly higher liver enzymes levels on admission. Conclusion-In Tunisia, gastrointestinal symptoms are often observed in severe scorpion envenomations, especially in young patients. In children, diarrhea and elevated liver enzymes are associated with poor prognosis. Objectives-To evaluate the type and incidence of gastrointestinal manifestations secondary to scorpion envenomation and their prognostic significance. Patients and methods-All patients admitted to our ICU for scorpion envenomation were included in this retrospective chart review of a 13-year period (1990-2002 Results-During the study period, 951 patients were admitted for scorpion envenomation and 72 (7.6%) died. Ages ranged from 0.5 to 90 years with a mean of 14.7 ± 17.4 years. Gastrointestinal symptoms were present in 700 patients (73.6% At univariate analysis, the presence of diarrhea was associated with a fatal outcome (P <0.05). Diarrhea was also found in 247 (2.5%), vomiting in 687 (72.2%) and diarrhea in 41 patients correlated with other indicators of severe envenomation and poor prognosis: respiratory failure (P = 0.01), neurological failure (P <0.0001), liver failure (P <0.0001) and low blood pressure requiring catecholamine support e analysis showed that young age (age less than 5 years), fever> 38.5 ° C, neurological failure and pulmonary edema were independent factors of severity. Digestive disorders were more frequent in children and in this subgroup diarrhea In a subset of patients for whom data were available, fatal cases demonstrated significantly higher in liver enzymes levels on admission. Conclusion-In Tunisia, gastrointestinal symptoms are often observed in severe scorpion envenomations, especially in young patients. In children, diarrhea and elevated liver enzymes are associated with poor prognosis
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