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目的:观察胃癌术后早期肠内营养支持的临床效果。方法:将76例患者随机分成早期肠内营养(EEN)组和未施行肠内营养(N-EEN)组(n=38),EEN组于胃癌术后24h经术中放置的鼻空肠管应用能全力进行早期肠内营养,N-EEN为术后静脉营养,术前、术后7天测定血清白蛋白、前白蛋白和体重、记录术后肠蠕动、排气时间和术后并发症。结果:两组肠鸣音恢复时间差异无统计学意义,EEN组术后肛门排气时间明显早于N-EEN组(P<0.05);两组术后体重均低于术前,但N-EEN组体重下降更明显,差异有统计学意义(P<0.05);术后第7天,两组患者血清白蛋白、前白蛋白均较术前下降,差异有统计学意义(P<0.05),但两组白蛋白下降的差异无统计学意义,而N-EEN组前清蛋白下降明显,差异有统计学意义(P<0.05)。结论:胃癌术后EEN安全、可靠,具有维护机体代谢平衡、促进肠蠕动的作用,并可减少术后并发症。
Objective: To observe the clinical effect of early postoperative enteral nutrition support for gastric cancer. Methods: 76 patients were randomly divided into early enteral nutrition (EEN) group and non-enteral nutrition group (n = 38). EEN group was given intranasal jejunal tube The patients were enrolled in this study. N-EEN was used for postoperative intravenous nutrition. Serum albumin, prealbumin and body weight were measured preoperatively and 7 days after operation. The postoperative peristalsis, time of vent and postoperative complications were recorded. Results: There was no significant difference in the recovery time of bowel sounds between the two groups. The postoperative anal exhaust time in EEN group was significantly earlier than that in N-EEN group (P <0.05) The weight loss of EEN group was more obvious, the difference was statistically significant (P <0.05). On the 7th day after operation, the levels of serum albumin and prealbumin in both groups were significantly lower than those before operation (P <0.05) , But there was no significant difference between the two groups in albumin decline, while the N-EEN group pregalactin decreased significantly, the difference was statistically significant (P <0.05). Conclusion: The postoperative EEN of gastric cancer is safe and reliable. It has the function of maintaining metabolism balance and promoting peristalsis, and can reduce postoperative complications.