论文部分内容阅读
目的探讨痰液嗜酸细胞检测在判断初次出现喘憋症状的下呼吸道疾病患儿预后中的临床应用价值。方法对100例初次出现喘憋症状的下呼吸道疾病患儿进行痰液嗜酸细胞测定,并按嗜酸细胞比例分为两组:≥5%为观察组,<5%为对照组。出院后对两组患儿均进行2年随访,分别记录发作人次、次数,比较其再喘发生率。随访期间,两组患儿均未给予预防性治疗。结果 62例嗜酸细胞增高者中再次喘息的患儿为43例,发生率为69.35%;38例非增高者中再次喘息的患儿为6例,发生率为15.79%。两组间差异有统计学意义(P<0.01)。结论痰液嗜酸细胞能较好地预测再喘的发生率,为有哮喘发展倾向的患儿提供了一个早期诊断、早期干预的人群选择指标,为早期治疗提供了客观依据。
Objective To investigate the clinical value of sputum eosinophil detection in predicting the prognosis of children with lower respiratory tract diseases with initial symptoms of wheezing. Methods The sputum eosinophils were measured in 100 children with lower respiratory tract symptoms of wheezing symptoms for the first time and divided into two groups according to the proportion of eosinophils: ≥5% for the observation group and <5% for the control group. After discharge, two groups of children were followed up for 2 years, respectively, record the number of attacks, times, compare the incidence of re-asthma. During the follow-up, no preventive treatment was given in both groups. Results In the 62 cases of eosinophilia, wheeze resumed wheezing in 43 cases, the incidence was 69.35%. Among the 38 cases of non-escalation, 6 cases resumed wheezing, the incidence was 15.79%. The difference between the two groups was statistically significant (P <0.01). Conclusion Sputum eosinophils can better predict the incidence of re-asthma, which provides an early diagnosis and early intervention population selection index for children with developmental tendency of asthma, which provides an objective basis for early treatment.