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不孕的原因很多,可在女方,男方或双方;但约有15~30%的不孕妇夫经系统检查找不出原因,后经免疫学检查,在双方或单方的血清及生殖道分泌物,如精子、精浆、宫颈粘液中发现抗精子抗体(下简称精子抗体)而造成不孕。这种由免疫学因素造成的不孕统称为“免疫不孕”。本文仅介绍其中的一个细节,即精子抗体与不孕。一、精子抗体的免疫机制精液中除精子和精浆外,还含男性生殖道的各种上皮细胞。就其抗原性,Rao等(1961)报道,人类精子有7种抗原,前列腺液有4种抗原,全精液中至少有16种抗
There are many reasons for infertility, the woman, the man or both; but about 15 to 30% of infertile women can not find the reason for the system examination, after immunological examination, both or unilateral serum and genital secretions , Such as sperm, seminal plasma, cervical mucus found in anti-sperm antibodies (hereinafter referred to as sperm antibodies) and cause infertility. This infertility caused by immunological factors collectively referred to as “immune infertility.” This article describes only one of the details, namely, sperm antibodies and infertility. First, the immune mechanism of sperm antibodies Sperm in addition to sperm and seminal plasma, but also contains a variety of male genital tract epithelial cells. For its antigenicity, Rao et al. (1961) reported that human spermatozoa have seven antigens, prostatic fluid has four antigens, and at least 16 antigens in total semen