CARMA3: A novel scaffold protein in regulation of NF-κB activation and diseases

• 作 者: Jiyuan Sun
• 出 处: 世界生物化学杂志：英文版（电子版）
• 发表日期: 2010年12期
• 关键词: G protein-coupled receptor Β-ARRESTIN CARD recruited membrane associated protein
• 基金项目: Supported by The National Institutes of Health through MD Anderson’s Cancer Center Support Grant, No. CA016672

CARD recruited membrane associated protein 3 (CARMA3) is a novel scaffold protein. It belongs to the CARMA protein family, and is known to activate nuclear factor (NF)- κB. However, it is still unknown which receptor functions upstream of CARMA3 to trigge