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作者对16例经用类固醇疗效不佳(包括8例部分有效者)的慢性型特发性血小板减少性紫癜(ITP)进行了脾切,着重探讨了脾切疗效及临床、实验可能的预测因素与脾切疗效的关系。结果:16例慢性型ITP,女性11例,男性5例,平均年龄为37±17岁。脾切后短期随访(1个月),11例(69%)完全缓解(Plt>150×10~9/L),4例(25%)部分缓解(plt50 150×10~9/L),1例无效(plt<50×10~9/L)。长期随访15例,平均时间为69个月,其中7例(47%)仍完全缓解,5例(34%)部分缓解,3例(20%)无效。无效组再用类固醇治疗,2例又获完全
The authors performed splenectomy on 16 patients with chronic idiopathic thrombocytopenic purpura (ITP) who had poor response with steroids (including 8 partially effective), and focused on the efficacy of splenectomy and possible clinical and experimental predictors Relationship with splenectomy. Results: Sixteen patients with chronic ITP, 11 women and 5 males, with an average age of 37 ± 17 years. Short-term follow-up of splenectomy (1 month) showed complete remission in 11 patients (69%), partial remission in 4 patients (25%), One case was invalid (plt <50 × 10 ~ 9 / L). Long-term follow-up of 15 cases, the average time was 69 months, of which 7 cases (47%) were still completely relieved, 5 cases (34%) partially relieved, 3 cases (20%) ineffective. Invalid group and steroid treatment, 2 patients were completely