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Objective To compare the clinical characteristics in a gonadotropin(Gn)and medroxyprogestrone acetate(MPA)protocol using three types of Gn in normal ovulatory women undergoing IVF/ICSI treatments.Methods A total of 258 normal ovulatory IVF/ICSI patients undergoing ovarian stimulation in a Gn and MPA protocol were analyzed in this retrospective study and allocated into three groups according to the Gn used:group A,hM G-A(brand name:Fengyuan,n=105);group B,hM G-B(brand name:Lebaode,n=90);group C:u-FSH(brand name:Lishenbao,n=63).The hormone profile,embryological characteristics,and the pregnant results after frozen-thawed embryo transfer(FET)were compared among the three groups.Results There was no significant difference in the number of oocytes retrieved among the three groups(12.1±6.9 vs 12.1±5.6 vs 13.1±8.8,P>0.05).Other indicators such as the number of mature oocyte,fertilization,cleavage and viable embryo were similar(P>0.05).No premature LH surges were detected,with a range of 0.04-7.38 IU/L.No differences were found in the clinical pregnancy rate per transfer(43.48%vs37.93%vs 40.74%,P>0.05)and the implantation rate(34.88%vs 22.22%vs 26.42%,P>0.05).Conclusion MPA is an effective oral alternative for the prevention of premature LH surges.Progestin-primed ovarian stimulation(PPOS)is a novel regimen of ovarian stimulation in combination with embryo cryopreservation,in which the two types of hM G are as effective as u-FSH.
Objective To compare the clinical characteristics in a gonadotropin (Gn) and medroxyprogestrone acetate (MPA) protocol using three types of Gn in normal ovulatory women undergoing IVF / ICSI treatments. Methods A total of 258 normal ovulatory IVF / ICSI patients undergoing ovarian stimulation in a Gn and MPA protocols were analyzed in this retrospective study and assigned into three groups according to the Gn used: group A, hM GA (brand name: Fengyuan, n = 105); group B, hM GB (brand name: Lebaode, The hormone profile, embryological characteristics, and the pregnant results after frozen-thawed embryo transfer (FET) were among among the three groups. Results There was was (90); group C: u-FSH no significant difference in the number of oocytes retrieved among the three groups (12.1 ± 6.9 vs 12.1 ± 5.6 vs 13.1 ± 8.8, P> 0.05) .Other indicators such as the number of mature oocyte, fertilization, cleavage and viable embryo were similar P> 0.05) .No premature LH surges were detected, with a range of 0. 04-7.38 IU / L.No differences were found in the clinical pregnancy rate per transfer (43.48% vs 37.93% vs 40.74%, P> 0.05) and the implantation rate (34.88% vs 22.22% vs 26.42%, P> 0.05 ) .Conclusion MPA is an effective oral alternative for the prevention of premature LH surges. Progestin-primed ovarian stimulation (PPOS) is a novel regimen of ovarian stimulation in combination with embryo cryopreservation, in which the two types of hM G are as effective as u-FSH.