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目的:了解青海地区(0~6)岁儿童的血清25羟维生素D水平,分析影响因素,为本地区制定补充维生素D策略提供参考。方法:分层随机选取西宁市城中区、西宁市城东区、湟中县、贵德县、德令哈市、格尔木市共6个采集点,实际检测869例。采用酶联免疫法测定25羟维生素D水平。结果:有效数据869例,婴儿组、幼儿组、学龄前组,中位数(P_(25),P_(75))分别是:48.9(47.7,72.2)、53.0(51.3,68.6)、50.0(47.5,66.6)。按照25羟维生素D适宜范围50nmol/L~250nmol/L评价,低于此标准的婴儿期、幼儿期、学龄前期分别为:29.0%、19.2%、30.7%。最大值为185.2nmol/L,没有1例超过250nmol/L。结论:青海省(0~6)岁儿童维生素D营养水平总体状况良好,且明显优于平原地区,对补服维生素D的需求并不高。
Objective: To understand the level of serum 25-hydroxyvitamin D in children aged 0-6 in Qinghai Province and to analyze the influencing factors so as to provide reference for the strategy of vitamin D supplementation in this area. Methods: Stratified randomly selected six collection points in Chengzhong District of Xining City, Chengdong District of Xining City, Chengzhong County, Guiding County, Delingha City and Golmud City, and 869 cases were actually detected. Enzyme-linked immunosorbent assay was used to determine 25-hydroxyvitamin D levels. Results: The data of 869 valid cases were 48.9 (47.7, 72.2), 53.0 (51.3, 68.6), 50.0 (51.3, 68.6) and infants, preschool children 47.5,66.6). In accordance with the appropriate range of 25 hydroxy vitamin D 50nmol / L ~ 250nmol / L evaluation, lower than this standard of infancy, early childhood, preschool were: 29.0%, 19.2%, 30.7%. The maximum value was 185.2 nmol / L and none of the cases exceeded 250 nmol / L. Conclusion: The nutritional status of vitamin D in children (0 ~ 6) in Qinghai Province is generally good and obviously superior to plain areas. The demand for vitamin D supplementation is not high.